Drug-induced tardive dyskinesia

Clozapine-induced Tardive Dyskinesia

Risperidone Induced Tardive Dyskinesia - a Case Report

Risperidone is a serotonin - dopamine antagonist which has got less propensity to cause tardive dyskinesia than conventional antipsychotics. There have been few reports of tardive dyskinesia induced by risperidone. This is a report of a case of risperidone induced tardive dyskinesia. A 56 year old female with a 6 months history of paranoid schizophrenia, developed bucco-oro-masticatory abnormal...

Treatment of neurolept-induced tardive dyskinesia

Tardive dyskinesia (TDK) includes orobuccolingual movements and "piano-playing" movements of the limbs. It is a movement disorder of delayed onset that can occur in the setting of neuroleptic treatment as well as in other diseases and following treatment with other drugs. The specific pathophysiology resulting in TDK is still not completely understood but possible mechanisms include postsynapti...

Metoclopramide and tardive dyskinesia.

Metoclopramide (MCP) is a D-2 receptor blocker (Kebabian and Calne 1979), which has been available by prescription in the United States since 1979 for use as an antiemetic in a wide range of situations. One of the common indications for MCP is the &eatment of diabetic gastroparesis (Physicians' Desk Reference 1993). A few recent reports suggest that diabetes mellitus may be a risk factor for ta...

Sulpiride in tardive dyskinesia.

The abnormal involuntary movements in tardive dyskinesia can be reduced by the dopamine antagonist drugs, phenothiazines and butyrophenones, but most cause an increase in Parkinsonian signs. Sulpiride, a benzamide derivative, and selective antagonist of D2 receptors had a significantly beneficial effect on most of 15 patients (p less than 0.01). In 12 patients the improvement was marked. The re...